Fluocinolone reduces inflammation, redness, and swelling, while suppressing pigment-stimulating pathways.
Hydroquinone inhibits melanin production, lightening hyperpigmented areas
Tretinoin accelerates skin cell turnover, enhances penetration of other actives, and helps disperse melanin
FDA-approved (as Tri-Luma in the US) for treating facial melasma
Intended for short-term use (up to 8 weeks) in conjunction with sun avoidance and sunscreen
Apply once nightly: gently cleanse the face, pat dry, and apply a pea-sized amount (covering affected areas plus a ½ inch margin) at least 30 minutes before bedtime
Use only external; avoid occlusive dressings and contact with eyes, mouth, or nose
Avoid sun exposure; daily use of broad-spectrum SPF 30+ sunscreen, hats, and protective clothing is essential.
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